2021 Schedule

AIMM / ASBMR John Haddad Young Investigators Meeting
Virtual (via Zoom) and In-Person at the Stonebridge Inn

Snowmass, Colorado, USA

Sunday, April 4th – Registration

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4:00pm – 7:00pm

Stonebridge Inn

Registration

More information about registration..

For more information about meeting registration…

Monday, April 5th – Welcome

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6:30am

Columbine Room, Stonebridge Inn

Registration Continues

More information about registration...

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6:55am

Columbine Room, Stonebridge Inn

Introduction & Welcome

By Kurt Hankenson, University of Michigan, AIMM President

Monday, April 5th – Session 1

PTH Action in Bone: “Back To The Future”

Chair: Larry Suva, Texas A&M

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7:30am - 8:10am

Columbine Room, Stonebridge Inn

The NACA transcriptional coregulator is an effector of PTH anabolism

By René St. Arnaud, McGill University and Shriners Hospital

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8:10am - 8:50am

Columbine Room, Stonebridge Inn

Salt inducible kinases dictate Pth1r action in bone and mineral metabolism

By Marc Wein, Harvard University

Break

8:50AM – 9:00AM

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9:00am - 9:20am

Columbine Room, Stonebridge Inn

Effects of standard versus high dose PTH in combination with denosumab on bone microarchitecture

By John Haddad Young Investigator: Sabashini Ramchand, Harvard – MGH

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9:20am - 9:40am

Columbine Room, Stonebridge Inn

Intermittent Parathyroid Hormone Treatment Reduces Marrow Adipose Tissue In Patients with Hypoparathyroidism

By John Haddad Young Investigator: Annegreet Veldhuis-Vlug, Leiden University Med Center

Mid-day Break

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4:00pm - 5:00pm

Columbine Room, Stonebridge Inn

Meet the Young Investigators

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5:00pm - 6:00pm

Columbine Room, Stonebridge Inn

Meet the Professor Break-Out 1: Non-rodent animal models to study the skeleton

By Dana Gaddy,Texas A&M

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5:00pm - 6:00pm

Columbine Room, Stonebridge Inn

Meet the Professor Break Out 2: Heterotopic ossification – how does bone form outside of the skeleton?

By Eileen Shore, University of Pennsylvania

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6:00pm - 8:00pm

Columbine Room, Stonebridge Inn

Meet – and – Greet (for in-person attendees)

Tuesday, April 6th – Session 2

Cutting Edge Genetics in Diagnosis and Treatment of Musculoskeletal Disease

Chair: Suzanne Jan de Beur, Johns Hopkins

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7:30am - 8:10am

Columbine Room, Stonebridge Inn

Application of New Genetic Technologies in the Clinic

By Ingrid Holm, Boston Children’s Hospital

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8:10am - 8:50am

Columbine Room, Stonebridge Inn

The Latest in Skeletal Dysplasias: Genetics, Phenotyping and Treatment

By Julie Hoover-Fong, Johns Hopkins

Break

8:50AM – 9:00AM

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9:00am - 9:20am

Columbine Room, Stonebridge Inn

Frizzled 2 and Craniofacial Bone Development: A Tale of Two Mouse Models

By John Haddad Young Investigator: Megan Michalski, Van Andel Institute

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9:20am - 9:40am

Columbine Room, Stonebridge Inn

Identifying Targets for Osteoporosis via Whole Exome Sequencing and CRISPR-Cas9

By John Haddad Young Investigator: Sirui Zhou, Lady Davis Institute of Jewish General Hospital

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9:40am - 10:00am

Columbine Room, Stonebridge Inn

Origin and Functions of Osteoclasts and Macrophages in Inflammatory Arthritis

By John Haddad Young Investigator: Christian Jacome-Galarza, Brigham and Women’s Hospital

Mid-day Break

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4:00pm - 5:00pm

Columbine Room, Stonebridge Inn

Young Investigator Mentoring Sessions – Break Out

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5:00pm - 6:00pm

Columbine Room, Stonebridge Inn

Meet the Professor Break-Out 1: Controversies in pharmaceutical treatment of patients with achondroplasia

By Julie Hoover-Fong, Johns Hopkins

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5:00pm - 6:00pm

Columbine Room, Stonebridge Inn

Meet the Professor Break Out 2: Career development: Starting your new
lab

By Joy Wu, Stanford University

Courtney Karner, University of Texas Southwestern

Wednesday, April 7th – Session 3

Novel therapies to target the bone marrow niche in cancer

Co-Chairs:

Melissa Kacena, Indiana University

Jesús Delgado-Calle, University of Arkansas Medical School

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7:30am - 8:10am

Columbine Room, Stonebridge Inn

Osteocytes and the bone/bone marrow niche of cancer in bone

By Terestia Bellido, University of Arkansas Medical School

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8:10am - 8:50am

Columbine Room, Stonebridge Inn

PTH actions in the breast cancer bone metastatic niche

By Joy Wu, Stanford University

Break

8:50AM – 9:00AM

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9:00am - 9:20am

Columbine Room, Stonebridge Inn

Remodeling our perspective on osteocytes: the link between bone and energy homeostasis

By John Haddad Young Investigator: Neha Dole, University of California, San Francisco

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9:20am - 9:40am

Columbine Room, Stonebridge Inn

Osteocyte-specific deletion of the auxiliary α2δ1 voltage sensitive calcium channel subunitimpairs femur strength and load-induced bone formation

By Charles H. Turner Young Investigator: Christian Wright, Indiana University

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9:40am - 10:00am

Columbine Room, Stonebridge Inn

Influence of Genetic Variability on Musculoskeletal Response to Unloading in Diversity Outbred Mouse Founder Strains

By AIMM Investigator: Michael Friedman, Virginia Commonwealth University

Mid-day Break

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4:00pm - 5:00pm

Columbine Room, Stonebridge Inn

Business Meeting

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5:00pm - 6:00pm

Columbine Room, Stonebridge Inn

Workshop: NIH initiatives to promote diversity in science

By Kristy Nicks, NIH – NIAMS

Thursday, April 8th – Session 4

Fracture repair, a model of regeneration: evolving concepts

Chair: Dan Bikle, University of California, San Francisco

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7:30am - 8:10am

Columbine Room, Stonebridge Inn

Fracture Nonunion: New Insights into Mechanism and Therapy

By Jie Shen, Washington University

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8:10am - 8:50am

Columbine Room, Stonebridge Inn

Life, Death and Transformation in the Transition Zone: an Emerging Model of Endochondral Ossification

By Ralph Marcucio, University of California, San Francisco

Break

8:50AM – 9:00AM

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9:00am - 9:20am

Columbine Room, Stonebridge Inn

From fish to fractures: Translational biology of Notch signaling

By John Haddad Young Investigator: Daniel Youngstrom, University of Connecticut Health Center

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9:20am - 9:40am

Columbine Room, Stonebridge Inn

The stem cell basis of bone versus fat formation

By John Haddad Young Investigator: Shawon Debnath, Weill Cornell Medical College

Mid-day Break

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4:00pm - 5:00pm

Columbine Room, Stonebridge Inn

Young Investigator Break Out Rooms – Scientific Discussions

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5:00pm - 6:00pm

Columbine Room, Stonebridge Inn

Meet the Professor Session 1: Management of low bone density in functional hypothalamic amenorrhea

By Madhu Misra, Harvard

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5:00pm - 6:00pm

Columbine Room, Stonebridge Inn

Meet the Professor Session 2: How to use the versatility of a FACS machine for bone and mineral research”

By Matthew Greenblatt, Weill Cornell Medical College

Friday, April 9th – Session 5

Neuropsychiatric disorders and medications: Impact on bone

Chair: Tamara King, University of New England

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7:30am - 7:50am

Columbine Room, Stonebridge Inn

Dances with bones: inter-tissue communication in the regulation of long bone growth

By John Haddad Young Investigator: Alberto Rosello-Diez, Monash University

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7:50am - 8:30am

Columbine Room, Stonebridge Inn

Impact of autism spectrum disorder and anorexia nervosa on bone in adolescents and young adults”

By Madhu Misra, Harvard

Break

8:30AM – 8:40AM

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8:40am - 9:20am

Columbine Room, Stonebridge Inn

Atypical antipsychotic drug effects on bone and metabolism: new insights after warming up the mice

By Katie Motyl, Maine Medical Research Center Institute (MMCRI)

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9:20am - 9:40am

Columbine Room, Stonebridge Inn

Vitamin D receptor signaling prevents the adverse actions of glucocorticoid excess in bone, skeletal muscle, and the heart, by interfering with the atrogene pathway

By John Haddad Young Investigator: Amy Sato, University of Arkansas Medical Center

Mid-day Break

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5:00pm - 7:00pm

Columbine Room, Stonebridge Inn

Strategic Planning Discussions

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